Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer

Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

Gisèle Bonne, Marina Raffaele di Barletta, Shaïda Varnous et al. · Nature Genetics · 1999 · 1.3K citations

Mendelian Disorder, Genetic Disorder, Genetics +3

Loss of a-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy

Teresa Sullivan, Diana Escalante‐Alcalde, Harshida Bhatt et al. · The Journal of Cell Biology · 1999 · 1.2K citations · Full text

Knockout Mouse, Developmental Biology, Skeletal Muscle +13

Lamin A-Dependent Nuclear Defects in Human Aging

Paola Scaffidi, Tom Misteli · Science · 2006 · 1.2K citations · Full text

Lifespan Extension, Chromatin, Genome Instability +13

Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy

Silvia Bione, Elena Maestrini, Stefano Rivella et al. · Nature Genetics · 1994 · 882 citations

Mendelian Disorder, Genetic Disorder, Natural Sciences +10

Lamins A and C but Not Lamin B1 Regulate Nuclear Mechanics

Jan Lammerding, Loren G. Fong, Julie Y. Ji et al. · Journal of Biological Chemistry · 2006 · 701 citations · Full text

Mechanobiology, Chromatin, Nuclear Fragility +14