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Antidiabetic Activity and Phytochemical Screening of Crude Extract of Stevia Rebaudiana in Alloxan-induced Diabetiis Rats
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Citations
12
References
2010
Year
NutritionNutraceutical IngredientPolyphenolicsStevia RebaudianaOxidative StressStevia Rebaudiana LeavesDaily Single DosePhytochemicalMetabolomicsPharmacologyPhytochemistryAlloxan-induced Diabetiis RatsHerbal MedicineDiabetesPhysiologyHerb-drug InteractionBlood Sugar LevelDiabetes MellitusMetabolismMedicineCrude Extract
Results of phytochemical tests showed presence of different kinds of phyto-constituents in aqueous, ether and methanol extract of Stevia rebaudiana leaves. Daily single dose (2.0 g/kg) administration of aqueous extract (A.E.), ether extract (E.E.) and methanol extract (M.E.) for 28 days of S. rebaudiana could not show any significant change in ALT and AST levels in rats. Blood sugar level was found to be decreased on day 28 in groups of rats treated with A.E., E.E. and M.E. of S. rebaudiana.
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