Comparative Study on the Effects of a Low Molecular Weight Heparin (CY 216) and Standard Heparin in Low Dosage on Experimental Venous Thrombosis

Abstract

In a venous thrombosis model in the rat obtained by ligation of the inferior vena cava, the effects of standard heparin and CY 216, a low molecular weight heparin fraction, are compared. At a dosage of less than 2 mg/kg b.w. CY 216 is an effective antithrombotic, whereas standard heparin is not.