Resection of locally advanced pancreatic cancer after downstaging with continuous-infusion 5-fluorouracil, mitomycin-C, leucovorin, and dipyridamole

Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil. The gastrointestinal tumor study group

C G Moertel, Stephen Frytak, R. G. Hahn et al. · Cancer · 1981 · 1K citations

Medicine, Oncology, Radiation Oncology +13

A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study.

J J Lokich, James D. Ahlgren, John J. Gullo et al. · Journal of Clinical Oncology · 1989 · 772 citations

Medicine, Oncology, Pharmacology +15

COMBINED 5-FLUOROURACIL AND SUPERVOLTAGE RADIATION THERAPY OF LOCALLY UNRESECTABLE GASTROINTESTINAL CANCER

C MOERTEL · The Lancet · 1969 · 739 citations

Medicine, Oncology, Radiation Oncology +12

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate

Daniel V. Santi, Charles S. McHenry, Hans Sommer · Biochemistry · 1974 · 621 citations

Life Sciences, Biochemistry, Molecular Biology +5

Pharmacologic Principles of Cancer Treatment.

Annals of Internal Medicine · 1983 · 304 citations

Medicine, Oncology, Pharmacology +14