Comparison Between ²⁰¹ Tl and ^99m Tc Sestamibi Uptake During Adenosine-Induced Vasodilation as a Function of Coronary Stenosis Severity

Abstract

Thus, with adenosine-induced hyperemic flow, both 201Tl and sestamibi significantly underestimated the magnitude of the flow disparity between stenotic and normal perfusion beds. The degree of underestimation was greater for sestamibi. The clinical implication of these experimental findings for vasodilator perfusion imaging remains to be determined, since factors such as greater redistribution and scatter with 201Tl could offset its advantages.