CD40 AND CD40 LIGAND (CD154) ARE COEXPRESSED ON MICROVESSELS IN VIVO IN HUMAN CARDIAC ALLOGRAFT REJECTION1,2

Abstract

Both CD40 and CD40L are expressed in vivo on infiltrating leukocytes and on microvascular endothelium in human cardiac allograft rejection. We suggest that endothelial cell CD40 and CD40L play a role in human cell-mediated immune responses such as cardiac allograft rejection.