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Synthesis and biological evaluation of 1-(isoxazol-5-ylmethylaminoethyl)-4-phenyl tetrahydropyridine and piperidine derivatives as potent T-type calcium channel blockers with antinociceptive effect in a neuropathic pain model

Pain TherapyMedicinal ChemistryPain MedicineMedicineNeuropathic PainPiperidine DerivativesNeuropharmacologyNeuropathic Pain ModelMolecular PainBiological EvaluationPain MechanismPharmacologyDrug DiscoveryPain Research