Concepedia

An ultrasensitive electrochemical impedance sensor for a special BRCA1 breast cancer gene sequence based on lambda exonuclease assisted target recycling amplification

Huifeng Xu, Lili Wang, Hongzhi Ye, Lishuang Yu, Xi Zhu, Zhenyu Lin, Guangwen Wu, Xihai Li, Xianxiang Liu, Guonan Chen

Chemical Communications · 2012 · 70 citations · 28 references

DOI

Concepts

Abstract

A label-free, target recycling electrochemical impedance spectroscopy (EIS) DNA sensor has been developed for detection of a model related to the BRCA1 breast cancer gene with a detection limit of 0.05 nM.

References

28

Electrochemical interrogation of conformational changes as a reagentless method for the sequence-specific detection of DNA

Chunhai Fan, Kevin W. Plaxco, Alan J. Heeger · Proceedings of the National Academy of Sciences · 2003 · 1K citations · Full text

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Electronic Aptamer‐Based Sensors

Itamar Willner, Maya Zayats · Angewandte Chemie International Edition · 2007 · 818 citations

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Electrochemical Coding Technology for Simultaneous Detection of Multiple DNA Targets

Joseph Wang, Guodong Liu, Arben Merkoçi · Journal of the American Chemical Society · 2003 · 611 citations

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Sequence-selective biosensor for DNA based on electroactive hybridization indicators

Kelly M. Millan, Susan Mikkelsen · Analytical Chemistry · 1993 · 549 citations

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Sensitive and Selective Amplified Fluorescence DNA Detection Based on Exonuclease III-Aided Target Recycling

Xiaolei Zuo, Fan Xia, Yi Xiao et al. · Journal of the American Chemical Society · 2010 · 492 citations

, , +15