Identification of Activating c-kit Mutations in Adult-, but not in Childhood-Onset Indolent Mastocytosis: A Possible Explanation for Divergent Clinical Behavior

Human proto‐oncogene c‐kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

Yosef Yarden, Wun-Jing Kuang, Teresa L. Yang‐Feng et al. · The EMBO Journal · 1987 · 1.6K citations · Full text

Life Sciences, Molecular Biology, Oncology +13

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

Benoı̂t Chabot, Dennis A. Stephenson, Verne M. Chapman et al. · Nature · 1988 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +12

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder.

H Nagata, A S Worobec, Chang Kyu Oh et al. · Proceedings of the National Academy of Sciences · 1995 · 880 citations

Life Sciences, Genetics, Hematology +16

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

Dirk Anderson, Stewart D. Lyman, Allison M. Baird et al. · Cell · 1990 · 857 citations

Life Sciences, Immunology, Molecular Biology +10

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

Krisztina M. Zsebo, Jette Wypych, Ian McNiece et al. · Cell · 1990 · 823 citations

Life Sciences, Cell Biology, Hematology +11