Metformin directly inhibits androgen production in human thecal cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.3K citations

Life Sciences, Biochemistry, Molecular Biology +12

Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome

Andrea Dunaif, Karen R. Segal, Walter Futterweit et al. · Diabetes · 1989 · 1.9K citations

Medicine, Endocrinology, Gynecology +11

Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.

David A. Ehrmann, Randall B. Barnes, Robert L. Rosenfield et al. · Diabetes Care · 1999 · 1.3K citations

Medicine, Endocrinology, Gynecology +11

Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome

D. Kiddy, Diana Hamilton‐Fairley, Anne Bush et al. · Clinical Endocrinology · 1992 · 922 citations

Medicine, Endocrinology, Gynecology +10

A Direct Effect of Hyperinsulinemia on Serum Sex Hormone-Binding Globulin Levels in Obese Women with the Polycystic Ovary Syndrome*

John E. Nestler, LINDA P. POWERS, Dennis W. Matt et al. · The Journal of Clinical Endocrinology & Metabolism · 1991 · 817 citations

Medicine, Endocrinology, Gynecology +17