Design and Synthesis of Polycyclic Imidazole‐Containing N‐ Heterocycles based on CH Activation/Cyclization Reactions

Abstract

Abstract A new strategy for the synthesis of polycyclic imidazole‐containing N‐heterocycles, based on the two general synthetic ways, namely the Pd(II)‐catalyzed intramolecular arylation via CH/CHal and CH/CH coupling reactions, was developed. The method proposed here enables the synthesis of many fused N‐heterocycles containing purine, 1‐deazapurines and benzimidazole structural units.