Concepedia

Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression

Hongli Liu, Shu-Ling Liang, Sheetal R Kumar, Crystal M. Weyman, Wendy Liu, Aimin Zhou

Cancer Chemotherapy and Pharmacology · 2008 · 81 citations · 33 references

DOI

Concepts

References

33

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

Brydon L. Bennett, Dennis T. Sasaki, Brion W. Murray et al. · Proceedings of the National Academy of Sciences · 2001 · 2.6K citations · Full text

, , +17

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

Omar A. Coso, M Chiariello, Jin‐Chen Yu et al. · Cell · 1995 · 1.6K citations · Full text

, , +9

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Audrey Minden, Anning Lin, François-Xavier Claret et al. · Cell · 1995 · 1.5K citations · Full text

, , +11

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K

Patricia J. Keely, John Westwick, Ian P. Whitehead et al. · Nature · 1997 · 731 citations

, , +12

The statins as anticancer agents.

Kelvin Chan, Amit M. Oza, Lillian L. Siu · PubMed · 2003 · 604 citations

, , +14