Concepedia

“On water” direct catalytic vinylogous Henry (nitroaldol) reactions of isatins for the efficient synthesis of isoxazole substituted 3-hydroxyindolin-2-ones

Yong Zhang, Biaowen Wei, Hui Lin, Ling Zhang, Jinxiang Liu, Haiqing Luo, Xiaolin Fan

Green Chemistry · 2015 · 47 citations · 44 references

DOI

Concepts

Abstract

An efficient “on water”-promoted direct catalytic vinylogous Henry reaction is described, giving products in excellent yields and diastereoselectivities.

References

44

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Sridhar Narayan, John Muldoon, M. G. Finn et al. · Angewandte Chemie International Edition · 2005 · 1.7K citations · Full text

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Hydrophobic acceleration of Diels-Alder reactions

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Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C‐3 Position

Feng Zhou, Yun‐Lin Liu, Jian Zhou · Advanced Synthesis & Catalysis · 2010 · 1.2K citations

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On the Theory of Organic Catalysis “on Water”

Yousung Jung, R. A. Marcus · Journal of the American Chemical Society · 2007 · 698 citations

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3-Substituted-3-hydroxy-2-oxindole, an Emerging New Scaffold for Drug Discovery with Potential Anti-Cancer and other Biological Activities

Satyamaheshwar Peddibhotla · Current Bioactive Compounds · 2009 · 508 citations

, , +10