Assays of drug sensitivity for cells from human tumours: in vitro and in vivo tests on a xenografted tumour

Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.

Emil J. Freireich, E. A. Gehan, David P. Rall et al. · PubMed · 1966 · 1.4K citations

Pharmacy, Oncology, Toxicology +14

Quantitation of Differential Sensitivity of Human-Tumor Stem Cells to Anticancer Drugs

Sydney E. Salmon, Anne W. Hamburger, B Soehnlen et al. · New England Journal of Medicine · 1978 · 974 citations

Medicine, Oncology, Pharmacology +16

An in vitro colony assay for human tumours grown in immune-suppressed mice and treated in vivo with cytotoxic agents

V D Courtenay, J. Mills · British Journal of Cancer · 1978 · 291 citations

Medicine, Cancer Biology, Oncology +10

Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function.

Robert S. Benjamin, Charles E. Riggs, Nicholas R. Bachur · PubMed · 1977 · 209 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Quantitative prediction of drug toxicity in humans from toxicology in small and large animals.

Michael Goldsmith, Milan Slavik, Stephen K. Carter · PubMed · 1975 · 133 citations

Medicine, Pharmacology, Toxicology +13