Organic & Biomolecular Chemistry · 2013 · 43 citations · 32 references
Natural SciencesChemistryMedicinal ChemistryCatalysisMass Spectrometric AnalysisSynthetic Medicinal ChemistryCalixarene ChemistryCatalytic MechanismsHeterocyclic ChemistryMass SpectrometryCalixarene FunctionalizationCalixarene SynthesisCatalytic CalixarenesMechanistic Pathway Reconstruction
A diastereoselective three-component cascade reaction, catalyzed by p-sulfonic acid calix[4]arene, provides a unique method to access diverse julolidine derivatives in high yields. Additionally, the reaction was also monitored by mass spectrometry and the mechanistic pathway uncovered.
32