A Randomized Trial of the Impact of Strict Glycaemic Control on Myocardial Diastolic Function and Perfusion Reserve: A Report from the DADD (Diabetes Mellitus and Diastolic Dysfunction) Study

Abstract

The hypothesis that strict glycaemic control would reverse early signs of MDD and improve CFR in patients with type 2 diabetes could not be confirmed, despite achieved normalization. Whether it is possible to influence a more pronounced diastolic dysfunction, particularly in less well-controlled diabetic patients, remains to be established.