Characterization of voltage operated R-type Ca2+ channels in modulating somatostatin receptor subtype 2- and 3-dependent inhibition of insulin secretion from INS-1 cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

Grzegorz Grynkiewicz, Martin Poenie, Roger Y. Tsien · Journal of Biological Chemistry · 1985 · 21.7K citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

Owen P. Hamill, Alain Marty, Erwin Neher et al. · Pflügers Archiv - European Journal of Physiology · 1981 · 18.5K citations

Natural Sciences, Biophysics, Cell Biology +16

Muscarinic activation of ionic currents measured by a new whole-cell recording method.

R Horn, Alain Marty · The Journal of General Physiology · 1988 · 1.8K citations · Full text

Medicine, Pharmacology, Physiology +17

Rapid Identification of Subtype-Selective Agonists of the Somatostatin Receptor Through Combinatorial Chemistry

Susan P. Rohrer, Elizabeth T. Birzin, Ralph T. Mosley et al. · Science · 1998 · 461 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).

Yogesh Patel, Coimbatore B. Srikant · Endocrinology · 1994 · 348 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14