Concepedia

Characterization of a novel aldose reductase inhibitor, FR74366, and its effects on diabetic cataract and neuropathy in the rat

Shizuo Ao, Yasuhiko Shingu, Chie Kikuchi, Yukiko Takano, Kazuhiko Nomura, Tatsujiro Fujiwara, Y. Ohkubo, Yoshitada Notsu, Isamu Yamaguchi

Metabolism · 1991 · 73 citations · 50 references

DOI

Concepts

References

50

Isolation and Properties of Lens Aldose Reductase

Selma Hayman, Jin H. Kinoshita · Journal of Biological Chemistry · 1965 · 560 citations · Full text

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Formation of Polyols by the Lens of the Rat with ‘Sugar’ Cataract

Ruth van Heyningen · Nature · 1959 · 435 citations

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Sorbitol Pathway: Presence in Nerve and Cord with Substrate Accumulation in Diabetes

Kenneth H. Gabbay, L Merola, R. A. Field · Science · 1966 · 399 citations

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Aldose Reductase Inhibition Improves Nerve Conduction Velocity in Diabetic Patients

Roman Judzewitsch, Jonathan B. Jaspan, Kenneth S. Polonsky et al. · New England Journal of Medicine · 1983 · 314 citations

, , +17

Regeneration and Repair of Myelinated Fibers in Sural-Nerve Biopsy Specimens from Patients with Diabetic Neuropathy Treated with Sorbinil

Anders A. F. Sima, Vera Bril, Virgil Nathaniel et al. · New England Journal of Medicine · 1988 · 294 citations

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