International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · 1968 · 40 citations · 9 references
MedicineCell BiologyOncologyRadiation BiophysicsRadiation DosimetryRadiobiologyBiological Effects Of RadiationCellular Radiation ResponseOxygen EffectRadiation BiologyRadiation SensitivityRelative Biological EffectivenessCell Survival AssaysCell Survival CurvesDose ResponseOxygen Enhancement RatioRadiobiological Oxygen DependenceRadiobiological ResponseRbe In Neutron RadiationRelative Effectiveness Estimation
SummaryThe effects of 14 meV monoenergetic neutrons were compared with those of 300 kV x-rays. Cell survival data were used to compute dose-response curves from which values of oxygen enhancement ratio (OER) and relative biological effectiveness (RBE) have been derived. The OER for HeLa cells was 1·51 with neutrons and 2·39 with x-rays; giving a gain factor of 1·58. The RBE for HeLa cells varied between a value of 4·3 at the 90 per cent level of cell survival to 2·3 at the 3 per cent level. The RBE can be assumed to fall to a constant value of 1·95 at lower levels of survival. A constant value of 1·9 was determined for the RBE for P388F mouse lymphoma cells.
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Clone-size Analysis in the Study of Cell Growth Following Single or during Continuous Irradiation
A.H.W. Nias, C. W. Gilbert, L. G. Lajtha et al. · International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · 1965 · 90 citations
Medicine, Biology, Cell Biology +17