The Journal of Antibiotics · 1990 · 63 citations · 12 references
PharmacyMedicinal ChemistryDrug DiscoveryNatural Product BiosynthesisEnzyme InhibitionFungal Natural Product BiosynthesisMicrobial Natural Product BiosynthesisPigment Biosynthesis InhibitionAnthocyanin Biosynthesis InhibitionMelanin BiosynthesisMelanin FormationMelanin ProductionMelanin Synthesis
A novel screening method for melanin biosynthesis inhibitors using Streptomyces bikiniensis NRRL B-1049 as the indicator organism has been developed. Several known compounds, including tyrosinase inhibitors, were found to inhibit melanin production of S. bikiniensis on agar plates. This screening method was applied to fermentation broths of actinomycetes and several cultures with melanin biosynthesis inhibitory activity were found.
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Bergey's Manual of Determinative Bacteriology
F. A. S., R. E. Buchanan, N. E. Gibbons et al. · Taxon · 1975 · 11.4K citations
Inhibition of mushroom tyrosinase by tropolone
Varda Kahn, Andrawis Andrawis · Phytochemistry · 1985 · 198 citations