Retina · 1992 · 52 citations · 0 references
MedicineAnatomyOphthalmologyOcular DiseaseOcular PathologyOphthalmic PathologyFoveal AnatomyMacular AnatomyOcular AlbinismRetinal AnatomyRetinal PathologyRetinal Pigment EpitheliumFoveolar RegionMacular HypoplasiaOcular HistopathologyOculocutaneous AlbinismRetinal Lipofuscin AccumulationUltrastructural CharacterizationUltrastructural CharactersUltrastructural Pathology
Histopathologic and ultrastructural findings in an eye from a patient with complete oculocutaneous albinism are reported. Examination revealed posterior embryotoxon, high myopia, no foveal differentiation, and absence of melanin pigment in all ocular structures. A few nonmembrane-bound electron-dense granules of lipofuscin were present in the iris and retinal pigment epithelial cells.