Rapid prenatal diagnosis by fluorescent in situ hybridization of chorionic villi: An adjunct to long-term culture and karyotype

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

D. Pinkel, J. E. Landegent, Colin C. Collins et al. · Proceedings of the National Academy of Sciences · 1988 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

A Morphological Distinction between Neurones of the Male and Female, and the Behaviour of the Nucleolar Satellite during Accelerated Nucleoprotein Synthesis

Murray L. Barr, Ewart G. Bertram · Nature · 1949 · 1K citations

Life Sciences, Cell Biology, Neuroscience +8

Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes

Thomas Cremer, Peter Lichter, Jonathan Borden et al. · Human Genetics · 1988 · 554 citations

Life Sciences, Genetics, Oncology +17

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

Thomas Cremer, J. E. Landegent, Andrea Brückner et al. · Human Genetics · 1986 · 372 citations

Life Sciences, Genetics, Molecular Genetics +16

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments

Thomas Cremer, Christoph Cremer, Hella Baumann et al. · Human Genetics · 1982 · 278 citations

Life Sciences, Cell Biology, Genetics +16