A Tracer Study with Mn56 on Chicks with Perosis Produced by a Synthetic Manganese Deficient Diet.

Abstract

Perosis has been produced in chicks reared on a synthetic manganese-deficient diet. Tracer experiments with labeled manganese show that the major part of the manganese, whether administered orally or by injection, is excreted by both the deficient and control chicks. The liver is the most active participant in the body in the metabolism of manganese. The uptake of labeled manganese by bone was not measurable when the dose was administered orally.