Molecular mechanisms of mistletoe plant extract-induced apoptosis in acute lymphoblastic leukemia in vivo and in vitro

Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis.

Heike Bantel, Ingo H. Engels, Wolfgang Voelter et al. · PubMed · 1999 · 196 citations

Life Sciences, Cell Biology, Oncology +17

In vitro effects of mistletoe extracts and mistletoe lectins. Cytotoxicity towards tumor cells due to the induction of programmed cell death (apoptosis).

A Scheffler, Dieter Kabelitz · PubMed · 1993 · 123 citations

Life Sciences, Immunology, Oncology +13

Modulation of programmed cell death by medicinal plants.

Urmila Thatte, S Bagadey, S A Dahanukar · PubMed · 2000 · 122 citations

Life Sciences, Botany, Pharmacology +11

Mistletoe viscotoxins increase natural killer cell‐mediated cytotoxicity

Julie Tabiasco, Frédéric Pont, Jean‐Jacques Fournié et al. · European Journal of Biochemistry · 2002 · 101 citations · Full text

Life Sciences, Immunology, Toxicology +13

Phase I trial of intravenous aviscumine (rViscumin) in patients with solid tumors: a study of the European Organization for Research and Treatment of Cancer New Drug Development Group

P. Schöffski, S. Riggert, P. Fumoleau et al. · Annals of Oncology · 2004 · 80 citations · Full text

Medicine, Oncology, Pharmacology +10