Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

Masato Orita, Hiroyuki Iwahana, Hiroshi Kanazawa et al. · Proceedings of the National Academy of Sciences · 1989 · 3.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Identification and characterization of the familial adenomatous polyposis coli gene

Joanna Groden, Andrew Thliveris, Wade S. Samowitz et al. · Cell · 1991 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +10

Identification of FAP Locus Genes from Chromosome 5q21

Kenneth W. Kinzler, Mef Nilbert, Li-Kuo Su et al. · Science · 1991 · 2.4K citations

Medicine, Genetics, Molecular Genetics +17

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

Isamu Nishisho, Yusuke Nakamura, Yasuo Miyoshi et al. · Science · 1991 · 1.9K citations

Life Sciences, Genetics, Oncology +17

Localization of the gene for familial adenomatous polyposis on chromosome 5

Walter F. Bodmer, Clyde Bailey, J. G. Bodmer et al. · Nature · 1987 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +11