Rapid Evolution of the Male-Specific Antibacterial Protein Andropin Gene in Drosophila

A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

Journal of Molecular Evolution · 1980 · 29.8K citations

Life Sciences, Biology, Evolutionary Biology +15

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions.

M Nei, T Gojobori · Molecular Biology and Evolution · 1986 · 5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Adaptive protein evolution at the Adh locus in Drosophila

John H. McDonald, Martin Kreitman · Nature · 1991 · 3.4K citations

Life Sciences, Evolutionary Biology, Genetics +12

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

Austin L. Hughes, Masatoshi Nei · Nature · 1988 · 2K citations

Life Sciences, Genetics, Molecular Genetics +16

Evolution by the birth-and-death process in multigene families of the vertebrate immune system

Masatoshi Nei, Xun Gu, T. Ya. Sitnikova · Proceedings of the National Academy of Sciences · 1997 · 816 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +17