Concepedia

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

Eugene V. Mosharov, Kristin E. Larsen, Ellen Kanter, Kester A. Phillips, Krystal Wilson, Yvonne Schmitz, David E. Krantz, Kazuto Kobayashi, Robert H. Edwards, David Sulzer

Neuron · 2009 · 541 citations · 57 references

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57

Mice Lacking α-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine System

Asa Abeliovich, Yvonne Schmitz, Isabel Fariñas et al. · Neuron · 2000 · 1.7K citations · Full text

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Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease

Étienne C. Hirsch, Ann M. Graybiel, Yves Agid · Nature · 1988 · 1.3K citations

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Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct

Kelly A. Conway, Jean‐Christophe Rochet, Robert M. Bieganski et al. · Science · 2001 · 1.1K citations

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‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease

C. Savio Chan, Jaime N. Guzmán, Ema Ilijić et al. · Nature · 2007 · 906 citations

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Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells.

R. Mark Wightman, Janusz Jankowski, Robert T. Kennedy et al. · Proceedings of the National Academy of Sciences · 1991 · 891 citations

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