Discovery of talatisamine as a novel specific blocker for the delayed rectifier K+ channels in rat hippocampal neurons

The Structure of the Potassium Channel: Molecular Basis of K ⁺ Conduction and Selectivity

D. Doyle, João H. Morais‐Cabral, Richard A. Pfuetzner et al. · Science · 1998 · 6.8K citations

Natural Sciences, Biochemistry, Biophysics +17

Mediation of Neuronal Apoptosis by Enhancement of Outward Potassium Current

Shan Ping Yu, Chen-Hsiung Yeh, Stefano L. Sensi et al. · Science · 1997 · 575 citations

Medicine, Neuroscience, Pharmacology +17

Mutations Affecting Tea Blockade and Ion Permeation in Voltage-activated K ⁺ Channels

Roderick MacKinnon, Gary Yellen · Science · 1990 · 567 citations

Natural Sciences, Biophysics, Pharmacology +17

Enhancement of Outward Potassium Current May Participate in β-Amyloid Peptide-Induced Cortical Neuronal Death

Shan Ping Yu, Z. Shadi Farhangrazi, Howard S. Ying et al. · Neurobiology of Disease · 1998 · 189 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Comparison of voltage-dependent potassium currents in rat pyramidal neurons acutely isolated from hippocampal regions CA1 and CA3

Rolf Klee, Eckhard Ficker, Uwe Heinemann · Journal of Neurophysiology · 1995 · 156 citations

Life Sciences, Neurobiology, Neuroscience +16