Concepedia

Resolution and asymmetric synthesis of 3-hydroxycarboxylic acids by using (–)-menthone as a chiral template

Toshiro Harada, Tetsuya Yoshida, Yasuhiro Kagamihara, Akira Oku

Journal of the Chemical Society Chemical Communications · 1993 · 15 citations · 17 references

DOI

Concepts

Abstract

1,3-Dioxan-4-ones 6and 7 derived from (–)-menthone can be utilized in resolution of 3-hydroxycarboxylic acids and asymmetric synthesis of 2-substituted 3-hydroxycarboxylic acids.

References

17

Über die Stereospezifität der α‐Alkylierung von β‐Hydroxycarbonsäureestern. Vorläufige Mitteilung

György Fráter · Helvetica Chimica Acta · 1979 · 256 citations

, , +6

Totally stereoselective additions to 2,6-disubstituted 1,3-dioxin-4-ones (chiral acetoacetic acid derivatives). Synthetic and mechanistic aspects of remote stereoselectivity

Dieter Seebàch, Juerg Zimmermann, Urs Gysel et al. · Journal of the American Chemical Society · 1988 · 129 citations

, , +9

Stereospezifische Synthese von (+)‐(3<i>R</i>, 4<i>R</i>)‐4‐Methyl‐3‐heptanol, das Enantiomere eines Pheromons des kleinen Ulmensplintkäfers (<i>Scolytus multistriatus</i>)

György Fráter · Helvetica Chimica Acta · 1979 · 119 citations

, , +11

.alpha. Deprotonation of .beta.-lactones - an example of a forbidden .beta. elimination

Johann Mulzer, Thomas Kerkmann · Journal of the American Chemical Society · 1980 · 90 citations

, , +5

Alkylations of (<i>R,R</i>)‐2‐<i>t</i>‐Butyl‐6‐methyl‐1,3‐dioxan‐4‐ones which are not Possible with Lithium Amides may be Achieved with a Schwesinger P4 Base

Thomas Pietzonka, Dieter Seebàch · Chemische Berichte · 1991 · 84 citations

, , +9