Annals of Otology Rhinology & Laryngology · 2011 · 221 citations · 17 references
MedicineOtolaryngologySurgeryOtolaryngologic SurgeryPediatric OtolaryngologyRhinologyChronic RhinosinusitisEndoscopic Sinus SurgeryNasal PolyposisNasal PolypsChronic Rhinosinusitis Without Nasal PolypsEndoscopic Sinus Surgery ComplicationsFrontal Sinus SurgeryKaplan-meier Survival EstimatesNasal Polyp SurgeryRefractory Chronic RhinosinusitisRevision Endoscopic Sinus SurgeryRevision Surgery Rates
OBJECTIVES: Chronic rhinosinusitis with nasal polyposis is often refractory to medical and surgical management, especially in patients with asthma and aspirin intolerance. We used a contemporary database to investigate recurrence and revision surgery rates following endoscopic sinus surgery. METHODS: We performed a cohort study using a survival analysis technique. Records were reviewed of 549 patients with nasal polyposis who underwent endoscopic sinus surgery over a 10-year period. The main outcome measure was disease-free and surgery-free survival following endoscopic sinus surgery, investigated with Kaplan-Meier analyses. RESULTS: Patients with Samter's triad were significantly more likely to have a recurrence and undergo a second surgery following recurrence (risk-odds ratio, 2.7; 95% confidence interval, 1.5 to 3.2; p < 0.01) than were patients without asthma or with only asthma from the triad. The presence of initial frontal sinus disease also increased the likelihood of revision surgery (risk-odds ratio, 1.6; 95% confidence interval, 1.2 to 1.8; p < 0.05). CONCLUSIONS: This is the first study to use survival analysis to document revision surgery rates following endoscopic sinus surgery. Revision surgery occurs at a high rate, especially in patients with asthma, Samter's triad, or frontal sinus disease. Patients should routinely be informed during clinical consultations about the likelihood of recurrence. Early intervention for frontal sinus disease may be considered.
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Max Samter · Annals of Internal Medicine · 1968 · 834 citations
Medicine, Immunology, Pharmacology +12
Prognostic factors, outcomes and staging in ethmoid sinus surgery.
Kennedy Dw · PubMed · 1992 · 594 citations
Medicine, Otolaryngology, Surgery +14
Recurrence Rates after Endoscopic Sinus Surgery for Massive Sinus Polyposis
Rhoda Wynn, Gady Har‐El · The Laryngoscope · 2004 · 263 citations
Medicine, Otolaryngology, Surgery +15