The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

Life Sciences, Molecular Biology, Neuroscience +14

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

Colin L. Masters, G. Simms, Nicola A. Weinman et al. · Proceedings of the National Academy of Sciences · 1985 · 4.4K citations · Full text

Life Sciences, Biochemistry, Neurology +17

Alzheimer's Disease: Cell-Specific Pathology Isolates the Hippocampal Formation

Bradley T. Hyman, Gary W. Van Hoesen, António R. Damásio et al. · Science · 1984 · 2.3K citations

Life Sciences, Neurobiology, Neuroscience +17

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

K. E. Wisniewski, Henryk M. Wı́sniewski, G. Y. Wen · Annals of Neurology · 1985 · 1.2K citations

Medicine, Neurology, Neuroscience +16

Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease.

R.C.A. Pearson, Margaret M. Esiri, R. W. Hiorns et al. · Proceedings of the National Academy of Sciences · 1985 · 1K citations · Full text

Medicine, Neurology, Neuroscience +16