Headache The Journal of Head and Face Pain · 1977 · 31 citations · 0 references
MedicineNeurologyPharmacologyNeuropharmacologyPain MedicinePsychopharmacologyHeadache DisordersHeadache ManagementMedication Side Effect ManagementMigraine PharmacotherapySerotonergic PharmacologyAcute Migraine TreatmentHeadache ProphylaxisMigraine PharmacologyMigraine ProphylaxisPreventive Headache TherapyPreventive Migraine TherapyPreventive Migraine Treatment
SYNOPSIS Pizotifen, a tricyclic antiserotonin agent and inhibitor of certain other biogenic amines, was effective in reducing the severity and frequency of migraine attacks, producing complete remission in some cases, in a double‐blind placebo controlled trial in 36 patients. Serious side effects were not reported during the trial period.