Disorazol A1, a highly effective antimitotic agent acting on tubulin polymerization and inducing apoptosis in mammalian cells

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

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Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action

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Pharmacy, Medicinal Chemistry, Pharmacology +10

Turbidimetric studies of the in vitro assembly and disassembly of porcine neurotubules

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Natural Sciences, Biophysics, Cell Biology +4

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

Daniel M. Bollag, Patricia A. McQueney, Jian‐Yong Zhu et al. · PubMed · 1995 · 686 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Epothilons A and B: Antifungal and Cytotoxic Compounds from Sorangium cellulosum (Myxobacteria). Production, Physico-chemical and Biological Properties.

Klaus Gerth, Norbert Bedorf, Gerhard Höfle et al. · The Journal of Antibiotics · 1996 · 628 citations

Life Sciences, Biochemistry, Microbiology +13