Therapeutic effects of the endothelin receptor antagonist Ro 48-5695 in the TNBS/DNBS rat model of colitis

Ireneusz T. Padol, JiaQing Huang, Cory M. Hogaboam, Richard H. Hunt

European Journal of Gastroenterology & Hepatology · 2000 · 22 citations · 0 references

Abstract

These data provide evidence for the involvement of endothelins in the pathophysiology of inflammatory bowel disease and support the possibility of exploring a new therapeutic approach.