An Unexpected and Severe Neurological Disorder with Permanent Disability Acquired During Short-course Treatment with Metronidazole

Abstract

A case is reported of permanent sensorimotor distal polyneuropathy combined with sensory hemisymptoms in a middle-aged woman after only 10 g of metronidazole given as 400 mg, three times daily for 9 d. The disability is still permanent after 22 months of observation. No other cause has been found.