The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr−/−-dependent allergy mouse model

Inflammatory cytokines in cystic fibrosis lungs.

Tracey L. Bonfield, James R. Panuska, Michael W. Konstan et al. · American Journal of Respiratory and Critical Care Medicine · 1995 · 704 citations

Inflammation, Inflammatory Cytokines, Fibrosis +11

Asthma and inflammation

A B Kay · Journal of Allergy and Clinical Immunology · 1991 · 568 citations

Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease

Richard N. Fedorak, Alfred Gangl, Charles O. Elson et al. · Gastroenterology · 2000 · 510 citations

Inflammation, Chronic Inflammatory Diseases, Mucosal Immunology +6

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

Barbara R. Grubb, Raymond J. Pickles, Hong Ye et al. · Nature · 1994 · 368 citations

Inefficient Gene Transfer, Pathogenesis, Viral Pathogenesis +7

Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis.

Tracey L. Bonfield, Michael W. Konstan, Peter Burfeind et al. · American Journal of Respiratory Cell and Molecular Biology · 1995 · 351 citations

Asthma, Inflammatory Lung Disease, Lung Inflammation +17