Naphthazarin derivatives (IV): synthesis, inhibition of DNA topoisomerase I and cytotoxicity of 2- or 6-acyl-5,8-dimethoxy-1,4-naphthoquinones

Cleavage of DNA by mammalian DNA topoisomerase II.

Leroy F. Liu, Thomas C. Rowe, K M Tewey et al. · Journal of Biological Chemistry · 1983 · 533 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei.

Leroy F. Liu, Kathryn G. Miller · Proceedings of the National Academy of Sciences · 1981 · 349 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Synthesis of Shikalkin (±Shikonin) and Related Compounds

Akira Terada, Yasuhiro Tanoue, Akira Hatada et al. · Bulletin of the Chemical Society of Japan · 1987 · 68 citations

Natural Sciences, Chemistry, Medicinal Chemistry +4

The 2- or 6-(α-Hydroxyalkyl- and α-Oxoalkyl)-5,8-dimethoxy-1,4-naphthoquinones from the Oxidative Demethylation of 2-(α-Hydroxyalkyl- and α-Oxoalkyl)-1,4,5,8-tetramethoxynaphthalenes with Cerium(IV) Ammonium Nitrate, and the Further Demethylations to Naphthazarins

Yasuhiro Tanoue, Akira Terada · Bulletin of the Chemical Society of Japan · 1988 · 49 citations · Full text

Natural Sciences, Chemistry, Bioorganic Chemistry +4

Cytotoxic effects of phenyl-hydroquinone and some hydroquinones on isolated rat hepatocytes

Yoshio Nakagawa, Peter Moldéust · Biochemical Pharmacology · 1992 · 36 citations

Pharmacy, Pharmacology, Toxicology +11