U-Small nuclear ribonucleoprotein (RNP)-reactive autoantibodies: Diagnostic testing and clinical interpretation

Mixed connective tissue disease-an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA)

Gordon C. Sharp, William S. Irvin, Eng M. Tan et al. · The American Journal of Medicine · 1972 · 1.8K citations

Life Sciences, Immunology, Internal Medicine +17

Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.

Livia Casciola‐Rosen, Douglas K. Miller, Grant J. Anhalt et al. · Journal of Biological Chemistry · 1994 · 420 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

I. Pettersson, M. Hinterberger, Tsuneyo Mimori et al. · Journal of Biological Chemistry · 1984 · 371 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Mixed connective tissue disease

Gordon C. Sharp · SpringerReference · 2011 · 197 citations

Medicine, Immunology, Pathology +15

The use of immunoblotting and immunoprecipitation of (U) small nuclear ribonucleoproteins in the analysis of sera of patients with mixed connective tissue disease and systemic lupus erythematosus: A cross‐sectional, longitudinal study

Ingvar Pettersson, Grace Wang, Elaine I. Smith et al. · Arthritis & Rheumatism · 1986 · 149 citations

Life Sciences, Immunology, Molecular Biology +15