Isolation of an active step I spliceosome and composition of its RNP core

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

Engineering, Rna Polymerase Ii, Isolated Mammalian Nuclei +19

The RNA world

W Gilbert · Nature · 1986 · 1.9K citations

Functional Genomics, Genetics, Rna Structure Prediction +6

Autoregulation of Polypyrimidine Tract Binding Protein by Alternative Splicing Leading to Nonsense-Mediated Decay

Matthew Wollerton, Clare Gooding, Eric J. Wagner et al. · Molecular Cell · 2004 · 406 citations · Full text

Transcriptional Regulation, Nonsense-mediated Decay, Molecular Biology +3

Small Nuclear Ribonucleoprotein Remodeling During Catalytic Activation of the Spliceosome

Evgeny M. Makarov, Olga V. Makarova, Henning Urlaub et al. · Science · 2002 · 368 citations

Chromatin, U5 Snrnp, Engineering +14

The Prp19p-Associated Complex in Spliceosome Activation

Shih‐Peng Chan, Der-I Kao, Wei-Yü Tsai et al. · Science · 2003 · 322 citations