Polymorphisms in lymphotoxin alpha and CD14 genes influence TNFα production induced by Gram-positive and Gram-negative bacteria

A Polymorphism* in the 5′ Flanking Region of the CD14 Gene Is Associated with Circulating Soluble CD14 Levels and with Total Serum Immunoglobulin E

Mauro Baldini, I. Carla Lohman, Marilyn Halonen et al. · American Journal of Respiratory Cell and Molecular Biology · 1999 · 847 citations

Life Sciences, Genetics, Immunology +5

Genetic and Environmental Influences on Premature Death in Adult Adoptees

T. I. A. Sørensen, G G Nielsen, P. Andersen et al. · New England Journal of Medicine · 1988 · 835 citations

Public Health, Genetics, Pediatrics +8

Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice

Alain Haziot, Enza Ferrero, Frank Köntgen et al. · Immunity · 1996 · 747 citations · Full text

Life Sciences, Immunology, Microbiology +17

Tumour necrosis factor (TNF) gene polymorphism influences TNF-α production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans

Édouard Louis, Denis Franchimont, Anthony Piron et al. · Clinical & Experimental Immunology · 1998 · 568 citations · Full text

Life Sciences, Immunology, Molecular Genetics +14

A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis

Frank Stüber, Frank Bokelmann, Ulrich F. Schade · Critical Care Medicine · 1996 · 552 citations

Life Sciences, Genetics, Molecular Genetics +15