Anesthesiology · 1971 · 94 citations · 0 references
MedicineNeurosciencePharmacologyPharmacodynamicsNeuromuscular BlockadeNeuromuscular Blocking AgentsNeuromuscular JunctionNeuromuscular Blocking Agent PharmacodynamicsSensitivity To Neuromuscular Blocking AgentsTetanic Fade
The relation between receptor occlusion by a competitive neuromuscular blocking agent and fade of an indirectly elicited tetanus at frequencies of 30, 100 and 200/sec has been determined. Tetanic fade at 30/sec returned to normal when one-fifth to one-quarter of the receptors became available, and t