Chemistry - A European Journal · 2011 · 78 citations · 33 references
Natural SciencesChemistryCatalysisOrganic ChemistrySynthetic Medicinal ChemistryAddition ReactionsHeterocycle SynthesisHeterocyclic ChemistryC-h Bond ActivationMild Reaction ConditionsNickel CatalysisNucleophilic CatalysisNucleophilic Reactivity
Nickeleophilic addition! The first example of a nickel-catalyzed direct intramolecular nucleophilic addition of aryl or vinyl chlorides to α-ketoamides through CCl bond activation is reported, which takes place under mild reaction conditions (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Haolun Jin, Jun’ichi Uenishi, William J. Christ et al. · Journal of the American Chemical Society · 1986 · 575 citations