Nickel‐Catalyzed Intramolecular Nucleophilic Addition of Aryl or Vinyl Chlorides to α‐Ketoamides Through CCl Bond Activation

Jin‐Xiu Hu, Hao Wu, Chuan‐Ying Li, Weijian Sheng, Yi‐Xia Jia, Jianrong Gao

Chemistry - A European Journal · 2011 · 78 citations · 33 references

Concepts

Abstract

Nickeleophilic addition! The first example of a nickel-catalyzed direct intramolecular nucleophilic addition of aryl or vinyl chlorides to α-ketoamides through CCl bond activation is reported, which takes place under mild reaction conditions (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

References

33