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Bioactive Saponins and Glycosides. X. On the Constituents of Zizyphi Spinosi Semen, the Seeds of Zizyphus jujuba MILL. var. spinosa HU (1): Structures and Histamine Release-Inhibitory Effect of Jujubosides A1 and C and Acetyljujuboside B.
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1997
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Histamine Release-inhibitory EffectBiochemistryMedicineHerbal MedicineNutraceutical IngredientJujubosides A1PhytopharmacologyPhytochemicalPhytochemistryPharmacologyHistamine ReleaseBioactive SaponinsSpinosa HuChromatography
New dammarane-type triterpene oligoglycosides, jujubosides A1 and C and acetyljujuboside B1 were isolated from Zizyphi Spinosi Semen, the seeds of Zizyphus jujuba MILL. var. spinosa Hu, together-with three known saponins. The structures of jujubosides A1 and C and acetyljujuboside B were determined on the basis of chemical and physicochemical evidence. Jujubosides A1 and C and acetyljujuboside B were found to inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody-reaction.