Antimicrobial Agents and Chemotherapy · 2003 · 24 citations · 12 references
MedicinePediatricsPharmacotherapyAntimicrobial PharmacotherapyOtologyPediatric OtolaryngologyAntimicrobial DosingOtitis MediaPediatric Antibiotic TherapyPediatric Antimicrobial TherapyPediatric Ear DisordersPediatric OtologyAcute Otitis Media ManagementAcute Otitis Media TreatmentEar Infections In ChildrenPediatric Infection TreatmentStreptococcus Species
Children with acute otitis media underwent tympanocentesis and were given a single dose of 30 mg of azithromycin/kg of body weight. At day 28, the overall clinical cure rate was 206 of 242 (85%). Clinical cure rates for patients infected with Streptococcus pneumoniae (67 of 76; 88%) and Haemophilus influenzae (28 of 44; 64%) were consistent with historical rates for the 5-day dosing regimen.
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Expanding indications for the new macrolides, azalides, and streptogramins.
Stephen H. Zinner, Lawrence S. Young, J Acar et al. · 1997 · 102 citations