Cartilage repair using mesenchymal stem cell (MSC) sheet and MSCs‐loaded bilayer PLGA scaffold in a rabbit model

Abstract

The novel method of incorporation of MSC sheet to PLGA/MCSs could enhance the ability of cartilage regeneration and integration between repair cartilage and the surrounding cartilage. Transplantation of autologous MSC sheet combined with traditional strategies or cartilage debris might provide therapeutic opportunities for improving cartilage regeneration and integration in humans.