ChemBioChem · 2007 · 32 citations · 27 references
Life SciencesBiochemistryMolecular BiologyCellular BiochemistryCellular MetabolismGlycobiologyCell-surface GlycansEndomembrane SystemGlycan RecognitionGlycan StructureGlycan-protein InteractionsGlycosylation PathwaysEndoplasmic Reticulum BiochemistryEndoplasmic Reticulum GlycosylationHsp70 Chaperone SystemLipid-linked Oligosaccharides
Where the dots go. GlcNAc-, galactose-, glucose-, and mannose-displaying CdTe quantum dots have been synthesized. We found that GlcNAc-displaying quantum dots were specifically accumulated in digitonin-permeabilized HeLa cells only in the presence of ATP. This finding supports the hypothesis that the HSP70 family in the endoplasmic reticulum has an affinity for the GlcNAc moiety.
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