Tumor Budding is a Strong and Reproducible Prognostic Marker in T3N0 Colorectal Cancer

Abstract

Tumor budding is a strong, reproducible, and independent prognostic marker of outcome that is easily assessed on hematoxylin and eosin slides. This may be useful for identifying the subset of T3N0M0 patients at high risk of recurrence who may benefit from adjuvant therapy.