Histopathologic Effects of Radiofrequency Catheter Ablation in Previously Infarcted Human Myocardium

Abstract

Catheter-based RF ablation of ischemic VT in humans causes lesions that initially resemble coagulation necrosis. This is followed by the development of an inflammatory infiltrate and, finally, the development of fibrosis. Repeated application of RF ablation may result in much larger lesions than have been previously reported.