Stereoselective antagonism of NMDA-stimulated noradrenaline release from rat hippocampal slices by MK-801

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

Mk-801 Binding Sites, Neurotransmitter, Psychopharmacology +18

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

Nabil A. Anis, Stephen C. Berry, N.R. Burton et al. · British Journal of Pharmacology · 1983 · 1.4K citations · Full text

Non-competitive antagonists of excitatory amino acid receptors

John A. Kemp, Alan C. Foster, Erik H.F. Wong · Trends in Neurosciences · 1987 · 499 citations

Functional Selectivity, Medicine, Physiology +5

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Psychotropic Medication, Psychopharmacology, Pharmacotherapy +18

Classification and nomenclature of phencyclidine and sigma receptor sites

Rémi Quirion, Robert Chicheportiche, Patricia C. Contreras et al. · Trends in Neurosciences · 1987 · 271 citations

Sigma Receptor Sites, Medicine, Functional Selectivity +5