The toxin Tx4(6-1) from the spider Phoneutria nigriventer slows down Na+ current inactivation in insect CNS via binding to receptor site 3

Improved tools for biological sequence comparison.

William R. Pearson, David J. Lipman · Proceedings of the National Academy of Sciences · 1988 · 11.3K citations · Full text

Life Sciences, Bioinformatics, Biology +15

Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poison.

R. Llinás, Mutsuyuki Sugimori, Jen‐Wei Lin et al. · Proceedings of the National Academy of Sciences · 1989 · 632 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Molecular Determinants of High Affinity Binding of α-Scorpion Toxin and Sea Anemone Toxin in the S3-S4 Extracellular Loop in Domain IV of the Na+ Channel α Subunit

John C. Rogers, Yusheng Qu, Timothy N. Tanada et al. · Journal of Biological Chemistry · 1996 · 412 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Selective Peptide Antagonist of the Class E Calcium Channel from the Venom of the Tarantula<i>Hysterocrates gigas</i>

R.W. Newcomb, Balázs Szőke, Andrew Palma et al. · Biochemistry · 1998 · 401 citations

Medicine, Neuroscience, Pharmacology +17

An improved vaseline gap voltage clamp for skeletal muscle fibers.

Bertil Hille, D. T. Campbell · The Journal of General Physiology · 1976 · 312 citations · Full text

Natural Sciences, Biophysics, Physiology +15